Welcome to the mind of David Sinclair, PhD , one of the world's leading scientific authorities on longevity, aging and how to slow its effects. David Sinclair Social: Instagram Twitter FacebookMatthew LaPlante's Social: TwitterTo stay up to date with David's work to democratize biological age testing and insights, visit tallyhealth.com.Timestamps:(00:00:00) Introducing Episode Seven: Aging of the Brain(00:04:39) Thanking the Sponsors(00:07:38) Ex-differentiation as a Driver of Aging(00:09:22) The Brain Ages Slowly(00:14:17) Cognitive Function and Plasticity(00:17:44) Three Longevity Pathways: mTOR, AMPK, and Sirtuins(00:23:26) Plant-based Diets and B-vitamins(00:28:32) Homocysteine, Plaque, and Vasculature(00:32:35) Fatty Acids(00:35:48) Physical Activity(00:39:14) Metformin(00:46:02) NAD Boosters(00:50:33) Increasing Blood Flor(00:53:20) Sleep(00:58:02) Overall Message: Keep your Brain Healthy(00:58:50) Next Weeks Episode and the Future of Medicine(01:01:21) Options for Subscription for SupportFor the full show notes, including the peer-reviewed studies, visit the Lifespan podcast website.Please note that Lifespan with Dr. David Sinclair is distinct from Dr. Sinclair's teaching and research roles at Harvard Medical School. (0:08:04) Caloric Restriction is an Evolutionarily Conserved Anti-Aging Strategy Life lessons from the smartest people on the planet. It could be that right now, the human race is having less sex than ever before. He prefers to follow the research wherever that may lead, even if it means putting himself in locations and situations most people would not want to be in. Please note that Lifespan with Dr. David Sinclair is distinct from Dr. Sinclair's teaching and research roles at Harvard Medical School. * Instagram Dr. David Sinclair Social: (0:00:00) Introducing Ep. * Facebook In the guest interview series Marisa speaks with mindset and success experts including Gabby Bernstein, L Making Sense of Science features interviews with leading medical and scientific experts about the latest developments in health innovation and the big ethical and social questions they raise. * https://www.patreon.com/davidsinclair (00:02:39) Expressing Gratitude to the Sponsors Thank you to our sponsors: He takes it for a cardiovascular condition that is common in his family. Our Patreon page: https://www.patreon.com/davidsinclair Mission: extend lifespan. (00:02:15) Thanks the Sponsors (00:39:28) Wearables and Individualized Health Tracking Upcoming episodes will cover: why aging is a disease, the impact of dietary choices, fasting and exercise on aging, how various supplements and prescription drugs can protect against aging, why cosmetic aging occurs and how to combat it, the benefits and advancements of biotracking, and the future of age reversal. Timestamps: The latest science behind various beautifying therapies is highlighted, including newer interventions like low-level laser therapy and platelet-rich plasma injections.Thank you to our sponsors: Athletic Greens - https://athleticgreens.com/sinclair Levels - https://levels.link/sinclair InsideTracker - https://insidetracker.com/sinclairOur Patreon page: https://www.patreon.com/davidsinclairLifespan book: https://amzn.to/3sUqurTDr. In this weeks episode, Dr. David Sinclair and co-host Matthew LaPlante zero in on drugs and supplements that have been reported to combat aspects of aging. How to Turn Anxiety Into a Superpower | Dr. Wendy Suzuki, Griot Baba Lumumba, Dr. Arthur Burnett & Dr. Segun Adebayo l The Carl Nelson Show, #113 Mental Models for Health Entrepreneurship Dr Ignacio Medrano (CEO Savana), A. Peter Bailey, Simeon Booker Muhammad & Senghor Baye l The Carl Nelson Show, #338 The Secrets To Living Your Longest, Healthiest Life with Dr Mark Hyman, #159 Dr. Anna Lembke: Between Pleasure and Pain, Dr. Clarence Lusane, Jovani Patterson & Sinclair Skinner l The Carl Nelson Show, #592 - Richard Shotton - 8 Fascinating Psychological Biases, How to Finish What Matters & Get More Free Time | Spotlight Convo. (00:43:30) Measuring Aging - Biological Age vs. Chronological Age (00:23:19) Cellular Senescence, Ultraviolet Light, and Skin Aging Lifespan book: https://amzn.to/3sUqurT Enjoy listening and please leave a rating, giving us feedback to make this podcast better! He is a professor in the Department of Genetics and a co-founder of several biotechnology companies. For Longevity | Episode 5. David Sinclair Social: Instagram Twitter FacebookTo stay up to date with David's work to democratize biological age testing and insights, visit tallyhealth.com.Matthew LaPlante's Social: TwitterTimestamps:(00:00:00) Kicking Off Episode Four: Longevity Molecules(00:02:15) Thanks the Sponsors(00:04:46) An An Additional Boost Beyond Adversity Mimetics(00:05:52) Drugs vs. To stay up to date with David's work to democratize biological age testing and insights, visit tallyhealth.com. (00:18:29) Skin and Biological Aging Join Dr. David Sinclair, Ph.D. in Lifespan, a popular health podcast that brings the cutting edge of aging and longevity science straight to you. * InsideTracker - https://insidetracker.com/sinclair Timestamps: Lifespan by David Sinclair. Dr Bessel van der Kolk is a professor of psychiatry at Boston University School of Medicine and President of the Trauma Research Foundation in Massachusetts. (00:00:00) Launching Episode Six: Combating Cosmetic Aging & Improving Skin, Nails & Hair In this special episode of Bulletproof Radio, microbiologist and geneticist David Sinclair, Ph.D., gives a thoroughly researched perspective on the coronavirus, plus concrete steps you can take and lifestyle changes you can make to potentially lower your own risk. The Lifespan with Dr. David Sinclair podcast, its employees, guests and affiliates assume no liability for the application of the information discussed.Special thanks to our research assistants, Adiv Johnson & Sarah Ryan. * InsideTracker - https://insidetracker.com/sinclair Lifespan book: https://amzn.to/3sUqurT (01:07:37) Todays Takeaways The Lifespan with Dr. David Sinclair podcast, its employees, guests and affiliates assume no liability for the application of the information discussed. (00:58:15) Next Weeks Episode: External Aging * Athletic Greens - https://athleticgreens.com/sinclair , Mollie Bell will also provide us with a Reparations update. There are cheat codes to get the brain to believe strange things, do strange things and change in ways you might not anticipate. (00:43:28) No Duh Stuff: Sun Damage, Smoking, Alcohol, and Bad Food The Lifespan with Dr. David Sinclair podcast, its employees, guests and affiliates assume no liability for the application of the information discussed. Welcome to Lifespan with Dr. David Sinclair. The Lifespan with Dr. David Sinclair podcast, its employees, guests and affiliates assume no liability for the application of the information discussed.Special thanks to our research assistants, Adiv Johnson & Sarah Ryan. Hear about the latest developments in aging research, lifestyle practices for longevity, exercise and nutrition science, and more. Copyright 2023 Apple Inc. All rights reserved. This podcast is distin In this episode, Dr. David Sinclair and co-host Matthew LaPlante discuss why we age. davidasinclair 4 yr. ago Some guy, that's an excellent question. Sirtuins. Supplements and Highlight Points In Episode 3 of the Lifespan Podcast, Dr. David Sinclair and Matthew LaPlante dive deeply into the science of non-dietary interventions that mimic adversity and promote health. (00:11:30) Wearable Monitors: A Dashboard for your Body Key takeaways: Dr. David Sinclair's core principles for aging and longevity include diet, exercise, and fasting. (00:11:33) NAD Boosters We are in a new age of sexlessness. Sinclair mainly discusses the science behind why we age and interventions for slowing and even reversing aging. The Lifespan with Dr. David Sinclair podcast, its employees, guests and affiliates assume no liability for the application of the information discussed. As they discuss different adversity mimetics, they also explain how these interventions influence aging at the molecular and physiological levels. Dr. David Sinclair Social: Getting us started Baltimore activist Lynn Pinder & Pastor Yerby discuss their Educational Initiative to benefi, When was the last time you felt awe? forced to suck s cock video. In Episode 3 of the Lifespan Podcast, Dr. David Sinclair and Matthew LaPlante dive deeply into the science of non-dietary interventions that mimic adversity and promote health. * Twitter (00:09:51) Thanking the Sponsors Unveiling the stories behind the very special people who have devoted their life to people. * Levels - https://levels.link/sinclair In Episode 6 of the Lifespan podcast, Dr. David Sinclair and co-host Matthew LaPlante discuss cosmetic aging and how to improve skin, nails, and hair. Each week Ill be featuring inspirational stories and pr, Each afternoon, kids walk through my neighborhood, on their way home from school, and almost all of them are walking alone, staring down at their phones. . (00:37:31) Exercise Recommendations (0:29:42) Focus on Time-restricted Feeding ( 16 Hours of Fasting) The Science of Looking Younger, Longer | Episode 6. Lifespan with Dr. David Sinclair is a new podcast from world renowned aging research doctor, David Sinclair, Ph.D. Dr. Sinclair is a professor of genetics and co-director of Harvard Medical School's Center for Biology of Aging Research. The latest science behind various beautifying therapies is highlighted, including newer interventions like low-level laser . If you don't like what Hollywood's execs tell you to like? #079 Blood-Brain Barrier Dysfunction in Alzheimers Disease and Dementia | Axel Montagne, Ph.D. Dr. David Horne & Finacial Expert Darnell Parker l The Carl Nelson Show, Dr. David Clark - Longdendale Lights & Earth Lights, #595 - 700k Q&A - Negative Self-Talk, Upcoming Live Tour & Ray Dalio, Microjoys: Finding Hope When Lifes Not Okay | Cyndie Spiegel, #594 - Dr Richard Wrangham - The Incredible Evolution Of Human Violence, Sadiki Bakari & Nuri Muhammad l The Carl Nelson Show, #339 BITESIZE | How to Live Your Best Life | Jake Humphrey, The Real Solution to Freeing Our Kids - and Ourselves - from Tech Addiction, with Gaia Bernstein. Professor Ampim will also contends Woodson was one of the first scholars to study the history of the African diaspora. Expect to lea, Have you ever felt overwhelmed or helpless in the face of anxiety? They begin by highlighting how different types of physical activity (i.e., low-intensity aerobic exercise, high-intensity aerobic exercise, and weight training) protect against age-related disease and enhance longevity. No credit card needed. Dr. David Sinclair Social: Episode 2: Poverty, inequa What causes aging? Interviews in Health/Life Sciences/BioTech Entrepreneurship, AI, WEB3 and Policy | Get in touch: pod@musty.io, The Knowledge Project Podcast is a rare opportunity to listen to the best in the world on every topic. 89,911 views 1 year ago Welcome to Lifespan with Dr. David Sinclair. Special thanks to our research assistants, Adiv Johnson & Sarah Ryan. (00:28:15) Collagen, Keratin, and Skin Health (00:53:20) Sleep The Lifespan with Dr. David Sinclair podcast, its employees, guests and affiliates assume no liability for the application of the information discussed.Special thanks to our research assistants, Adiv Johnson & Sarah Ryan. (00:00:00) Introducing Episode Eight: The Future of Anti-aging Medicine Hear about the latest developments in aging research, lifestyle practices for longevity, exercise and nutrition science, and more. (00:33:40) NAD and Cancer (00:06:48) Modern Healthcare, Disease Detection, and Circulating DNA Professor, Harvard Medical School. New episodes will be released every Wednesday morning of both January and February 2022. (00:13:24) Survival Sensors (i.e., mTOR, AMPK, and Sirtuins) & Communicators (e.g., Insulin) They talk about why superficial aging occurs and how external signs of aging are often a reflection of biological age. (00:01:01) A Pernicisous Element Called Iron We need to start with the diet, then add the pills. This show is produced by Midland Care. Given the abundance of data available, a special focus is placed on the NAD precursors nicotinamide riboside and nicotinamide mononucleotide. (00:13:32) Nicotinamide Riboside (00:10:09) Human Growth Hormone In this episode, Dr. David Sinclair and co-host Matthew LaPlante discuss how frequently we should eat, what food we should avoid, and what food we should pursue. Before Brother Peter, Journalist Simeon Booker Muhammad will discuss Malcolm's importance to o, My guest today is someone who has been leading a global health revolution around using food as medicine to support longevity, energy, mental clarity and happiness. * Instagram Is it about happiness, health, friendship, love, or meaning? Guests: Labours Jon Cruddas MP; human rights activist Peter Tatchell; ConservativeHome editor Jonathan Isaby, psephologist Professor John Curtice; Dr Madsen Pirie, Director of the free-market Adam Smith Institute; LibDem Voice editor Stephen Tall; David Babbs of campaign organisation 38 Degrees, and the New Statesmans Laurie Penny. And, just kind of walk away, leaving something that couldve been amazing unfinished? In this weeks exciting episode of the Lifespan podcast, Dr. David Sinclair and co-host Matthew LaPlante foray into potential anti-aging interventions that are truly on the cutting edge. Hosted by award-winning journalist Tim Samuels. The information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. David Sinclair is a now professor in the Department of Genetics and co-director of the Paul F. Glenn Center for the Biology of Aging at Harvard Medical School. A password will be e-mailed to you. (00:16:42) Organisms with Extreme Longevity To celebrate, I asked for questions from YouTube, Twitter, Locals and Instagram, so here's another 90 minutes of me trying to answer as many as possible. This podcast can also be found on all podcast platforms, including Apple Podcasts and Spotify. Company. This podcast is distinct from Dr. Sinclair's teaching and research roles at Harvard Medical School. (0:51:44) The Okinawa Diet and Blue Zones You are right that proving lifespan extension isn't simple but it's possible. Or, may, Griot Baba Lumumba returns to our classroom to provide some thought-provoking topics for us to discuss. * Levels - https://levels.link/sinclair The information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. They share the latest experimental and clinical data for NAD boosters, resveratrol, fisetin, quercetin, rapamycin, spermidine, metformin, and berberine. Previous research on aging and DNA mutations. (00:04:46) An An Additional Boost Beyond Adversity Mimetics He is also the author of the best-selling book Lifespan: Why We Age & Why We Don't Have To, and is the host of the Lifespan Podcast. Hear about the latest developments in aging research, lifestyle practices for longevity, exercise and nutrition science, and more. (00:17:25) Get Off Your Butt Please note that Lifespan with Dr. David Sinclair is distinct from Dr. Sinclair's teaching and research roles at Harvard Medical School. (01:03:06) Putting in the Work for Longevity To stay up to date with David's work to democratize biological age testing and insights, visit tallyhealth.com. New episodes will be released every Wednesday morning in both January and February 2022. Marco has been prominently featured in every major media outlet from Good Morning America to Vogue and today marks his third appearance on the podcast. Timestamps: For Longevity | Lifespan With Dr. David Sinclair. Our Patreon page: https://www.patreon.com/davidsinclair To start the program, Baltimore activists Kim Poole & Sister Swatara Olushola live in Rwanda. Before we hear from Baba Lumumba, we'll review the increasing rate of Prostate Cancer among Black men. Sinclair told The Washington Post that he was taking 1000 mg of resveratrol a day when he was 45 in 2015 and still had a biological age of 58 according to what he recently revealed in an interview. (01:01:55) Options for Subscription and Support His book Lifespan: Why We Age and Why We Don't Have To is available now. Please subscribe, share with friends, leave a comment or review, and most of all, thank you for coming with us on this journey into the mechanisms of aging and exploration of the tools for living longer, healthier lives. Can you live a good life even when things are hard? Ground-breaking, Peabody Award-winning broadcast news journalist Carl Nelson, has interviewed Presidents, Prime Ministers, Heads of State, politicians, authors, celebrities, civic leaders, and people from all walks of life over a four-decade career that has taken him from Nelson Mandelas prison cell in South Africa to the Rodney King Riots in Los Angeles, to his present career as the host of Washington DCs latest daily newsmaker radio program weekdays from 6-10 am on WOL 1450am, WOLB Talk 2023 House / Tech / Progressive / Deep / Melodic / Techno / Edm / Afro / ibiza DJ Mix / Set / Podcast / Electronic Dance Music Radio Tomorrowland workout club 2022 party playlist beach tribal tiesto top best Defected 2021 Beats. What to Eat & When to Eat for Longevity | Episode 2. (00:07:38) Ex-differentiation as a Driver of Aging Correction and clarification: At time point 1:07:37, Dr. Sinclair says he takes 1 gram of Spermidine, but the active ingredient in the capsules is 1-2 milligrams. #591 - Critical Drinker - Why Does Modern Cinema Suck So Much? Thank you to our sponsors: They share the latest research surrounding testosterone replacement therapy (TRT), human growth hormone (HGH), peptide supplementation, exosomes, stem cells, and cellular reprogramming. Dr. Sinclair's book, Lifespan. * Twitter To stay up to date with David's work to democratize biological age testing and insights, visit tallyhealth.com. * InsideTracker - https://insidetracker.com/sinclair Leave your condolences to the family on this memorial page or send flowers to show you care. (00:39:14) Metformin (00:51:35) Resetting the Aging Clock Over the last 589 episodes, 1000+ hours and nearly 2000 days of working away on this project I've learned a lot, and today I'm going through some of the most important lessons and, What if you were, unknowingly being controlled by unresolved pain from your past, even minor, or momentary experiences, ones that took root and, from that moment on, without you having any idea, limited everything from your relationships to your health, work, wealth, and life? Don't snack. What does it mean to live a good life? (00:57:24) Cold Therapy (00:41:48) Optimizing Exercise and Activity-mimetics In this episode, Dr. David Sinclair and co-host Matthew LaPlante discuss why we age. For the full show notes, including the peer-reviewed studies, visit the Lifespan podcast website. royal military police ranks. David Sinclair has mentioned that he has added this important supplement to his stack in recent podcasts. David Sinclair Social: Instagram Twitter FacebookMatthew LaPlante's Social: TwitterTo stay up to date with David's work to democratize biological age testing and insights, visit tallyhealth.com.Timestamps:(00:00:00) Launching Episode Six: Combating Cosmetic Aging & Improving Skin, Nails & Hair(00:02:54) Estrogen, Progesterone, and Menopause(00:09:51) Thanking the Sponsors(00:12:57) The Pinch Test, Epidermal Thinning, and Foot Ulcers(00:18:29) Skin and Biological Aging(00:23:19) Cellular Senescence, Ultraviolet Light, and Skin Aging(00:28:15) Collagen, Keratin, and Skin Health(00:33:38) A Quick Aside about Nails(00:34:45) Autophagy and Retinoids(00:36:57) Resveratrol, NAD Boosters, and Hyaluronic Acid(00:41:44) Botox, Skin Peels, and Microneedling(00:43:28) No Duh Stuff: Sun Damage, Smoking, Alcohol, and Bad Food(00:45:42) Hair Loss and Hair Graying(00:49:45) Topical Treatments, Pills, and Dihydrotestosterone(00:55:19) Frickin Laser Beams: Low-level Laser Therapy(00:57:59) Platelet-rich Plasma (PRP) Injections(01:00:11) Hair Aging, Stress, and Gray Hair Reversal(01:06:11) Targeting Aging Upstream(01:07:37) Todays Takeaways(01:09:25) Subscription and Support OptionsFor the full show notes, including the peer-reviewed studies, visit the Lifespan podcast website.Please note that Lifespan with Dr. David Sinclair is distinct from Dr. Sinclair's teaching and research roles at Harvard Medical School. 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